👨⚕️ Speaker:
Vahan Grigoryan, M.D. , orthopaedist-traumatologist, tissue engineer. 🎓 Alma mater: Yerevan State Medical University (M.D. degree obtained in 2018, Orthopaedist/Traumatologist narrow specialization degree obtained in 2021). Currently serves as the head of the Department of Science of the University of Traditional Medicine of Armenia, Ph.D. student and junior researcher at L.A. Orbeli Institute of Physiology NAS RA. Co-Founder of Foldink Corp., an Armenian-American 3D bioprinting company founded in 2019. Member of the Board of Trustees of Kochard Foundation. 🏥 Past experience: volunteer of the Armenian Red Cross Society 2013-2021, 3D modeler in Locator CJSC 2011-2015.
📄 Summary:
The problem of peripheral nervous tissue defects (aka nerve gaps) in nerve ruptures is of considerable scientific interest in modern medicine. Such tissue defects can occur as a result of a number of injuries. If the nerve layers’ continuity is maintained or restored after being severed, these layers begin to serve as regenerative tunnels for the regenerating axons. Otherwise, nerve regeneration can become very challenging or virtually impossible. In the absence of a nerve defect or in case of very small defects, the nerve needs to be sutured end-to-end. In the case of larger defects, however, a nerve graft is needed, and autografting is the golden standard. Yet, it is associated with problems such as limited donor sites, the need for additional surgery, possible scarring, donor site morbidity, neuroma formation at the donor site, as well as the possibility of graft mismatch. In the case of allo- or xenografts, as it is known, there is a risk of graft rejection, thus immunosuppression is needed which poses the patient under substantial infection-related risks.
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